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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA1430
All Species:
1.52
Human Site:
T251
Identified Species:
4.17
UniProt:
Q9P2B7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2B7
NP_065878.1
532
59475
T251
Y
P
E
E
S
E
D
T
V
T
D
V
S
P
L
Chimpanzee
Pan troglodytes
XP_001163296
528
58990
V251
S
E
D
T
V
T
D
V
S
P
L
S
T
P
D
Rhesus Macaque
Macaca mulatta
XP_001084789
529
59268
D251
E
S
E
D
T
V
T
D
V
S
P
L
S
T
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPR1
541
60818
N261
D
Y
H
E
S
E
G
N
V
P
D
I
T
P
L
Rat
Rattus norvegicus
Q66H34
548
61724
D273
V
T
P
A
S
T
P
D
S
S
P
A
Q
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507043
345
36646
R100
L
P
T
V
A
S
S
R
L
G
S
G
P
A
S
Chicken
Gallus gallus
XP_001232315
269
29262
E24
Y
E
S
D
F
G
E
E
E
K
K
T
E
E
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997943
449
50583
T204
S
P
V
K
H
Q
R
T
S
S
A
D
Q
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796877
508
56869
E236
D
S
Y
R
D
S
N
E
R
R
A
K
G
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
95.4
N.A.
N.A.
70.4
69.7
N.A.
24.6
20.2
N.A.
27.8
N.A.
N.A.
N.A.
N.A.
26.3
Protein Similarity:
100
97.1
97.3
N.A.
N.A.
80
79.7
N.A.
36.6
31.3
N.A.
44.5
N.A.
N.A.
N.A.
N.A.
44.7
P-Site Identity:
100
13.3
20
N.A.
N.A.
46.6
13.3
N.A.
6.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
46.6
N.A.
N.A.
60
20
N.A.
20
20
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
12
0
0
0
0
0
23
12
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
23
0
12
23
12
0
23
23
0
0
23
12
0
0
12
% D
% Glu:
12
23
23
23
0
23
12
23
12
0
0
0
12
12
12
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
12
12
0
0
12
0
12
12
0
0
% G
% His:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
0
0
0
12
0
0
0
0
0
12
12
12
0
12
0
% K
% Leu:
12
0
0
0
0
0
0
0
12
0
12
12
0
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
12
% N
% Pro:
0
34
12
0
0
0
12
0
0
23
23
0
12
45
23
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
0
0
23
0
0
% Q
% Arg:
0
0
0
12
0
0
12
12
12
12
0
0
0
12
0
% R
% Ser:
23
23
12
0
34
23
12
0
34
34
12
12
23
0
12
% S
% Thr:
0
12
12
12
12
23
12
23
0
12
0
12
23
12
0
% T
% Val:
12
0
12
12
12
12
0
12
34
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
23
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _